Diffusion NMR spectroscopy

Diffusion NMR spectroscopy.

MR offers unique tools for measuring molecular diffusion. This review focuses on the use of diffusion-weighted MR spectroscopy (DW-MRS) to non-invasively quantitate the translational displacement of endogenous metabolites in intact mammalian tissues. Most of the metabolites that are observed by in vivo MRS are predominantly located in the intracellular compartment. DW-MRS is of fundamental inte...

Li Diffusion in LiAlO2 Single Crystals Studied with NMR Spectroscopy

γ-LiAlO2 crystallizes in the tetragonal space group P41212. A unit cell of this crystal contains four formula units and has lattice parameters a = (5.1687 ± 0.0005) Å and c = (6.2679 ± 0.0006) Å [1]. There are four crystallographically equivalent sites for the Li as well as for the Al atoms which, however, can be discriminated by NMR via the orientation of a single crystal with respect to an ex...

Measuring Molecular Motion Using NMR Spectroscopy to Study Translational Diffusion

This chapter demonstrates how to use NMR spectroscopy to measure the rate of translational diffusion. Once measured, this rate can provide insight into the size and shape of the molecules in a sample and can even be used to match peaks in the NMR spectrum with the different components of a sample mixture. Of the possible applications of diffusion, the experiment presented focuses on using measu...

Gradient-Diffusion Methods for Simulating Decoherence by NMR Spectroscopy

Theoretical techniques are developed for designing nuclear magnetic resonance (NMR) experiments to simulate a variety of adiabatic decoherence (aka T2 relaxation) processes, using sequences of pulsed field gradients and diffusion periods. To this end an efficient Hadamard product formalism is introduced and used to derive Lindblad master equations from NMR pulse sequences for both collective an...

NMR-Spectroscopy in Drug Analysis Quantitative NMR Spectroscopy